Table 1. Demographics and group characteristics.

	Controls	RR	SP	PP	All-MS
Number of subjects	24	27	26	18	71
Age [years]	36.0 (9.5)	35.1 (7.3)	41.7 (5.1)	41.2 (6.5)	39.1 (7.0)
Disease duration [years]	-	6.9 (4.2)	14.3 (6.1)	6.7 (3.1)	9.5 (6.0)
Median EDSS (range)	-	2 (0.0–6.0)	4.8 (2.5–7.0)	4.0 (2.5–7.0)	4.0 (0.0–7.0)
ROI T2-LL (%)	-	19.7 (11.3)	28.9 (15.2)	39.0 (20.6)	28.0 (17.1)
Brain T2-LL (%)	-	0.14(0.09)	0.29(0.24)	0.61(0.33)	0.60(0.41)

Values are expressed as mean (Standard deviation).

RR: relapsing remitting; SP: secondary progressive; PP: primary progressive; EDSS: expanded disability status scale; ROI T2-LL: T2-lesion load corresponding to the lesion volume measured within the region of interest (ROI); Brain T2-LL: T2-lesion load corresponding to the lesion volume measured in the whole brain.