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. 2012 Mar 30;7(3):e34055. doi: 10.1371/journal.pone.0034055

Figure 6. siRNA mediated knockdown of RNA sensors modulates KU812 responses to antibody-enhanced dengue virus infection.

Figure 6

Following knockdown of the indicated genes by siRNA transfection, KU812 cells were mock treated or exposed to infectious dengue virus with subneutralizing concentration of dengue-immune sera (1∶10,000). At 24 hours post-infection supernatants were harvested and analyzed for CCL4, CCL5 and CXCL10 content by ELISA. Graphs show the mean ± SEM of 4 separate experiments. ns, not significant; *P<0.05; **P<0.01, ***P<0.001.