Table 1. qPCR arrays reveal upregulation of anti-viral signaling molecules, receptors and mediators in dengue virus-infected CBMCs.
| Gene | Fold-increase in mRNA expression/mock | Gene | Fold-increase in mRNA expression/mock | ||
| Dengue+Ab | UV-Dengue+Ab | Dengue+Ab | UV-Dengue+Ab | ||
| PKR | 11.3 | 1.3 | IRF7 | 14.1 | 1.4 |
| OAS1 | 108.0 | 2.8 | IRF9 | 5.9 | 1.4 |
| OAS2 | 243.2 | 4.8 | IFNAR1 | 1.0 | 1.0 |
| MDA5 | 25.3 | 1.3 | IFNAR2 | 0.8 | 1.2 |
| RIG-I | 22.6 | 1.0 | IFNA4 | 36.7 | 0.7 |
| LGP2 | 17.4 | 1.8 | IFNA2 | 303.4 | 0.3 |
| IPS-1 | 1.0 | 1.0 | IFNB1 | 366.1 | 1.2 |
| TLR3 | 24.1 | 1.2 | MX1 | 648.7 | 9.4 |
| TLR7 | 3.8 | 1.0 | CCL2 | 9.7 | 2.2 |
| TLR8 | 1.0 | 1.0 | CCL3 | 27.4 | 2.4 |
| TICAM1 | 2.1 | 1.1 | CCL4 | 78.5 | 2.8 |
| MYD88 | 4.0 | 1.1 | CCL5 | 76.4 | 1.2 |
| TOLLIP | 1.1 | 1.0 | CCL8 | 9886.9 | 11.4 |
| NFKB1 | 2.3 | 1.1 | CCL11 | 0.7 | 0.6 |
| NFKB2 | 1.1 | 0.8 | CCL17 | 1.2 | 0.9 |
| JUN | 0.9 | 1.3 | CCL24 | 0.6 | 1.8 |
| IRF1 | 2.5 | 1.0 | CXCL8 | 3.4 | 1.9 |
| IRF3 | 1.0 | 1.0 | CXCL10 | 93347.6 | 43.0 |
Bold numbers indicate ≥2-fold higher levels of mRNA for the respective gene.
LGP2, laboratory of genetics and physiology 2; IPS-1, IFN-β promoter stimulator-1; TICAM1, Toll-like receptor adaptor molecule; TOLLIP, Toll interacting protein.