Figure 8. Dynamic behavior of MD-4 and immune B cells in the granuloma microenvironment.

Labeled MD-4 and immune B cells were transferred into d21-infected T^red mice as described in Figure 7. At 12–30 h post adoptive transfer, time lapse z-stack videos were prepared, and each B cell was manually tracked in Volocity software to determine (A) displacement, (B) velocity, (C) track length, (D) displacement rate and (E) meandering index. Data are shown for each individual B cell analyzed within 28 granulomas from two mice.