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. 2012 Mar 30;7(3):e34149. doi: 10.1371/journal.pone.0034149

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Hirai et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Schematic drawings of the VP16-tagged Oct4s, called VL16LO and VL16SO. Numbers indicate amino acid positions of VP16. (B) Formation of iPSCs from MEFs with two VP16-Oct4 fusion genes and SKM. (C) Virus titer of each construct measured with quantitative RT-PCR. Mean ± SEM from three independent experiments is shown. (D) Formation of iPSCs from MEFs without c-Myc.