Table 2. Total, new and recurrent tuberculosis (TB) incidence rates according to duration of antiretroviral therapy.
ART Duration(month) | Total TB episodes | PY at risk | Rate (per 100 PY) [95% CI] | Newa TB episodes | PY at risk | Rate (per 100 PY) [95% CI] | Recurrent TBb episodes | PY at risk | Rate (per 100 PY) [95% CI] | % recurrent TB [95% CI] |
0–12 | 174 | 1400 | 12.43 [10.82–14.35] | 46 | 438 | 10.49 [7.88–14.26] | 128 | 962 | 13.31 [11.33–15.74] | 73.6 [66.4–79.9] |
12–24 | 84 | 1252 | 6.71 [5.48–8.30] | 29 | 375 | 7.74 [5.44–11.38] | 55 | 878 | 6.27 [4.88–15.74] | 65.5 [54.3–75.5] |
24–36 | 70 | 1138 | 6.15 [4.90–7.82] | 15 | 323 | 4.65 [2.86–8.08] | 55 | 816 | 6.75 [5.23–8.86] | 78.6 [67.1–87.5] |
36–48 | 68 | 1023 | 6.64 [5.30–8.44] | 15 | 282 | 5.32 [3.25–9.29] | 53 | 741 | 7.15 [5.55–9.38] | 77.9 [66.2–87.1] |
48–60 | 49 | 899 | 5.45 [4.18–7.25] | 7 | 242 | 2.89 [1.41–6.90] | 42 | 657 | 6.39 [4.81–8.70] | 85.7 [72.8–94.1] |
>60 | 39 | 793 | 4.92 [3.64–8.62] | 9 | 202 | 4.45 [2.37–9.33] | 30 | 591 | 5.08 [3.59–7.42] | 76.9 [60.7–88.9] |
Overall | 484 | 6506 | 7.44 [6.82–8.13] | 121 | 1862 | 6.50 [5.41–7.84] | 363 | 4644 | 7.81 [7.06–8.68] | 75.0 [70.9–78.8] |
ART, antiretroviral therapy; TB, tuberculosis; PY, person-years; CI, confidence intervals.
no previous episodes of TB, a time-updated variable.
any previous episodes of TB, including prior to ART enrolment, a time-updated variable.