Table 1. Semi-quantitative evaluation of histological damage by a modified non-parametric scoring system in BIA and CIA mice.
Intimal hyperplasia | Subintimal fibrosis | Lymphocytic infiltration | Articular damage | |
Control | 0 | 0 | 0 | 0 |
BIA | +++ | 0 | +++ | 0 |
CIA | ++++ | 0 | +++ | 0 |
Note: The histological damage was scored after 28 d for articular sections of modeling mice, in which BIA was induced by daily bacterial feeding; and CIA was developed by twice immunizations (primary challenge and boosting).