Table 1. Semi-quantitative evaluation of histological damage by a modified non-parametric scoring system in BIA and CIA mice.

	Intimal hyperplasia	Subintimal fibrosis	Lymphocytic infiltration	Articular damage
Control	0	0	0	0
BIA	+++	0	+++	0
CIA	++++	0	+++	0

Note: The histological damage was scored after 28 d for articular sections of modeling mice, in which BIA was induced by daily bacterial feeding; and CIA was developed by twice immunizations (primary challenge and boosting).