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. 2012 Mar 30;7(3):e34402. doi: 10.1371/journal.pone.0034402

Table 4. Mitochondrial Respiration.

Control DHA ARA DHA+ARA
Pyruvate+Malate
State 3 225±17 239±22 245±21 236±19
State 4 (−oligomycin) 51.6±2.0 51.3±3.1 47.3±2.6 49.7±3.7
State 4 (+oligomycin) 36.8±4.1 44.8±4.3 33.7±3.6 41.1±4.3
RCR (−oligomycin) 4.5±0.4 4.7±0.4 4.8±0.2 5.2±0.4
RCR (+oligomycin) 6.8±0.8 5.8±0.6 8.1±0.9 6.2±0.6
Palmityl-CoA+Carnitine+Malate
State 3 221±16 203±14 200±14 196±13
State 4 (−oligomycin) 45.6±2.9 53.4±5.0 46.0±2.6 46.6±2.9
State 4 (+oligomycin) 40.9±3.8 41.2±4.7 36.4±2.8 42.9±4.3
RCR (−oligomycin) 5.0±0.3 4.1±0.4 4.3±0.3 4.5±0.4
RCR (+oligomycin) 5.7±0.4 6.4±1.7 5.8±0.5 5.1±0.6
Succinate+Rotenone
State 3 392±16 398±19 360±22 393±25
State 4 (−oligomycin) 122.7±3.6 120.1±7.3 111.6±4.7 108.2±6.9
State 4 (+oligomycin) 107.8±4.9 123.9±7.8 100.0±8.3 123.6±7.0
RCR (−oligomycin) 3.2±0.1 3.4±0.2 3.7±0.2 3.2±0.2
RCR (+oligomycin) 3.7±0.1 3.3±0.1 3.8±0.3 3.2±0.1

Data are the mean ± SEM. CTRL, n = 14. DHA, n = 13. ARA, n = 13. DHA+ARA, n = 14. All Rates are expressed in ng atoms O·mg−1·min−1. The RCR, defined as the ratio of State 3 to State 4 respiration rate, was calculated from the State 4 rate with oligomycin.