Fig. 2.

Biomarkers of selenium status in humans. A scheme of traditional and molecular biomarkers measurements with the impact of potential modifiers (physiological, environmental, genetic). The optimal selenium biomarker should reflect all putative egzo- and endogenous factors which can modulate selenium bioavailability, metabolism and selenoprotein transcription, biosynthesis, transport, activity and function. A type of measurement used for the determination of selenium status should be also considered