Figure 4.
Intestinal microbiota mediate cardioprotection via leptin. A) Quantified changes in 11 of 23 cytokines. B) Leptin reconstitution reversed cardioprotection by vancomycin. Rats were treated with leptin (0.12 μg/kg i.v.) at 24 and 12 h before myocardial ischemia/reperfusion. Data are means ± sd; n = 6/group. *P < 0.05 vs. control.
