Figure 5.
Goodbelly juice decreased leptin and protected against myocardial infarction. Dahl S rats were treated with Goodbelly (15 ml/rat/d) for 14 d before blood leptin analysis and myocardial ischemia/reperfusion. A) Goodbelly reduced myocardial infarction that was reversed by leptin reconstitution (0.12 μg/kg at 24 and 12 h before ischemia). B) Leptin levels in blood were decreased following Goodbelly treatment. C) L. plantarum levels increased in feces of Goodbelly-treated rats using quantitative PCR of 16S rRNA. Limit of detection for L. plantarum is 3 log10/g feces. Data are means ± sd; n = 6/group. *P < 0.01 vs. control.