Table 2.
Characteristics of the PD cases and controls included in analysis.
| Site | Type | Gender | Age, years (range) | PMI, hours (range) | Tissue pH (range) | PD Duration, years (range) |
|---|---|---|---|---|---|---|
| HBSFRC | 2 C | 2M | 86.5 (80–93) | 19.5 (13–26) | 6.41 (6.26–6.55) | N/A |
| 17 PD | 9F/8M | 82.2 (63–95) | 16.3 (9–37) | 6.30 (6.02–6.62) | 11.5 (4–28) | |
| BTRC | 39 C | 39M | 61.4 (36–106) | 21.9 (10–39.6) | 6.71 (5.95–7.32) | N/A |
| 35 PD | 35M | 76.3 (64–95) | 17.9 (6.6–30.7) | 6.50 (5.86–7.13) | 11.2 (3–23) | |
| SHRI | 23 C | 13F/10M | 84.3 (63–97) | 2.68 (1–5.5) | 6.71 (6.29–7.13) | N/A |
| 49 PD | 11F/38M | 78.5 (64–90) | 3.11 (1–10) | 6.59 (6.17–7.44) | 10.4 (0–40) | |
| All | 64 C | 13F/51M | 70.5 (36–106) | 14.9 (1–39.6) | 6.70 (5.95–7.32) | N/A |
| 101 PD | 20F/81M | 78.3 (63–95) | 10.4 (1–37) | 6.51 (5.86–7.44) | 10.9 (0–40) | |
| Final C Set* | 46 C | 13F/33M | 77.2 (58–97) | 11.7 (1–39.6) | 6.67 (5.95–7.32) | N/A |
C: Control; PD: Parkinson disease.
HBSFRC = Human Brain and Spinal Fluid Resource Center VA West Los Angeles Healthcare Center.
HBTRC = Harvard Brain Tissue Resource Center, McLean Hospital, Belmont, Massachusetts.
SHRI = Sun Health Research Institute in Sun City, Arizona.
*after removing controls with age at death ± 5 years beyond age at death of cases (< age 58 or > age 100).