Table 3.

Various intrapleural fibrinolytics (Adapted from Colice et al. [7]).

Fibrinolytic	Dose	Instillation	Duration
Streptokinase	250,000 IU	100–200 cc NS	QD for up to 7 days
Urokinase	10,000 IU	100 cc NS	QD for up to 3 days
t-PA	10–25 mg	100 cc NS	BID for up to 5 days

t-PA: tissue plasminogen activator.

IU: international units.

NS: normal saline.

QD: every day.

BID: twice a day.