Table 1.
Polymorphism frequency among patients and controls.
| Genotypes | Patients (RP + NR) (%) | CN (%) | p-value |
| HTR2A C516T | |||
| CC | 48 (81.4) | 26 (92.9) | 0.16 |
| CT | 11 (18.6) | 2 (7.1) | |
| TT | 0 (0) | 0 (0) | |
| HTR2A T102C | |||
| TT | 17 (28.3) | 6 (20.0) | <0.001 |
| TC | 43* (71.7) | 14* (46.7) | |
| CC | 0** (0) | 10** (33.3) | |
| HTR1B G681C | |||
| CC | 6 (10.2) | 2 (6.9) | 0.88 |
| CG | 24 (40.7) | 12 (41.4) | |
| GG | 29 (49.2) | 15 (51.7) | |
| Alleles | |||
| HTR2A C516T | 0.18 | ||
| C | 107 (90.7) | 54 (96.4) | |
| T | 11 (9.3) | 2 (3.6) | |
| HTR2A T102C | 0.007 | ||
| T | 77 (64.2) | 26 (43.3) | |
| C | 43 (35.8) | 34 (56.7) | |
| HTR1B G681C | 0.69 | ||
| C | 36 (30.5) | 16 (27.6) | |
| G | 82 (69.5) | 42 (72.4) |
Note: RP = Responders; NR = Non-responders; CN = Controls. *p = 0.02 after a chi-square partition for heterozygosity; **p<0.001 after a chi-square partition for the CC genotype.