Table 3.
Treatments | Dose (mg/kg) | Duration of study (h)
|
||||||
---|---|---|---|---|---|---|---|---|
t0b | t0a | 0.5 | 1 | 2 | 3 | 24 | ||
Control | - | 35.2 ± 0.3 | 35.4 ± 0.1 | 35.5 ± 0.2 | 35.3 ± 0.3 | 35.2 ± 0.1 | 35.0 ± 0.5 | 35.5 ± 0.3 |
N. latifolia | 16 | 35.1 ± 0.2 | 35.1 ± 0.4 | 35.3 ± 0.2 | 34.5 ± 0.1 | 34.4 ± 0.1 | 34.1 ± 0.1* | 35.3 ± 0.1 |
N. latifolia | 40 | 35.1 ± 0.2 | 35.4 ± 0.3 | 35.3 ± 0,5 | 34.4 ± 0.2* | 34.3 ± 0.1* | 34.2 ± 0.1* | 35.2 ± 0.1 |
N. latifolia | 80 | 35.1 ± 0.3 | 35.2 ± 0.2 | 35.2 ±0.2 | 34.3 ± 0.1** | 34.2 ± 0.1** | 34.1 ± 0.1* | 35.1 ± 0.3 |
N. latifolia | 160 | 35.2 ± 0.3 | 35.1 ± 0.3 | 35.1 ± 0.4 | 34.3 ± 0.1** | 34.2 ± 0.1** | 34 ± 0.1** | 35.1 ± 0.1 |
Results are expressed as mean ± S.E.M., t0b = initial body temperature, t0a = body temperature after the administration of the different treatment, the changes in temperature were expressed as the difference between the reference point and the value of rectal temperature after the injection of the extract or distilled water, n = 6 each group,
P<0.05,
P<0.05, significantly different compared to the control group, by two-way Anova followed Tukey’s (HSD) multicomparaison test.