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. 2001 Apr 17;98(9):5122–5127. doi: 10.1073/pnas.091095198

Figure 1.

Figure 1

Mutations in the yeast POL3 gene. The 1097-aa yeast POL3 ORF is shown schematically as a black bar. Names and positions of conserved regions are designated as in ref. 53. Gray boxes, conserved regions, other than nuclease; black boxes, exonuclease conserved regions. Consensus sequences of the 3′→5′ exonuclease signature motifs (7) are shown in brackets. Ts mutations are shown above and Exo mutations below the POL3 gene. Amino acid changes in different mutant alleles are shown in the table.