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Aberrant fiber cell migration in Epha2−/− lenses. Two-month-old lenses were stained with FM 4-64 and were visualized in the equatorial aspect by confocal microscopy. In wild-type lenses, fiber cells project toward the posterior pole. In contrast, Epha2−/− fiber cells deviate from their normal course, curving away from the pole and terminating at mislocalized posterior suture branches. E, epithelium. Scale bar, 250 μm.
