Table 1.
Parameter | Description | Value | Source |
---|---|---|---|
β | Baseline transmission rate of the sensitive infection | variable | |
1/µE | Expose period (duration between exposure and start of infectiousness) | 1.25 days | [4,15-18] |
1/γ | Duration of infectiousness | 4 days | [4,15,16,18,19] |
α | Rate of developing drug resistance following start of treatment | 10-4 days-1 | [16,18] |
δT | Relative transmissibility of the sensitive infection following treatment | 0.4 | [15,16,18,20] |
δr | Relative transmissibility of the resistant infection | 0.8 | [15,16,18] |
p | Fraction of infectious individuals diagnosed for treatment or isolation | variable | |
q | Fraction of treated infectious individuals without isolation | variable | |
Tc | Capacity for treatment and isolation of infectious individuals | variable | |
R0 | Basic reproduction number of the sensitive infection | variable | [3,19,20] |
Baseline values of the parameters used for simulations of the models with sources from published literature. For a given value of R0, the baseline transmission rate β can be calculated using the expression R0 = βS0/γ.