Table 2.

Independent preoperative predictors of mortality (logistic regression analysis) and the deriving scoring system for mortality prediction in native valve IE.

	B coeff.	OR (95% CI)	P	Score
Age
40–49 years				5
50–59 years		1.042 (1.015–1.020)		7
60–69 years	0.041		0.002	9
70–79 years				11
≥80 years				13
Renal failure1	1.076	3.033 (1.338–6.876)	0.013	5
NYHA class IV	1.777	5.913 (2.569–13.612)	<0.001	9
Ventilatory support2	2.281	9.784 (3.178–30.117)	<0.001	11
Positivity of latest pre-op. blood culture3	1.093	2.982 (1.304–6.821)	0.010	5
Perivalvular involvement4	1.110	3.033 (1.338–6.876)	0.008	5

¹Creatinine >2 mg/dL.

²Patients admitted to the Cardiac Surgery Department on mechanical ventilation (intubated) or requiring ventilatory support by noninvasive ventilation during preoperative stay (generally for poor hemodynamic conditions and/or pulmonary edema).

³This variable identified operation without possibility of previous attainment of negative cultures by antibiotic therapy (latest culture had always been performed within 5 to 7 days preoperatively).

⁴Either annular abscess or aortocavitary fistula.