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. 2012 Mar 12;2012:307571. doi: 10.1100/2012/307571

Table 3.

Definition of the 4 risk groups according to total score and comparisons in terms of clinically relevant variables.

Class 1 Class 2 Class 3 Class 4 P
Total score range 0–5 7–131 14–19 ≥20

Mean predicted mortality 1 ± 0.7% 3.7 ± 1.6% 12 ± 5% 43 ± 18%

Age (years) 34 ± 9 55 ± 13 52 ± 17 64 ± 11 <0.001

Sex (female) 30% 20% 37% 39% 0.06
Active IE 81% 79% 91% 89% 0.08

Site: Aortic 47% 44% 51% 41% 0.03
 Mitral 27% 27% 16% 22%
 Tricuspid 6% 11% 9% 9%
 Mitroaortic 11% 16% 21% 26%
 Other 9% 2% 3% 2%

NYHA class IV 1.7% 52% 59% <0.001

Diabetes 3% 12% 22% 18% <0.001

Renal failure 4% 8% 27% 39% <0.001

Period: before 2000 39% 40% 14% 7% 0.003
    2000–2010 26% 42% 16% 16%

Positive latest preop. culture 5% 17% 19% 44% <0.001

Perivalvular involvement 4% 12% 27% 44% <0.001

Preop. ventilatory support 6% 30% <0.001

Emergency 0.7% 4% 22% 59% <0.001

Infection persistence postop. 2% 2% 9% 29% <0.001

1Note that the 6-point score cannot be obtained by any sum of scores in this system.