Table 2. Molecular pathways related to the genes commonly modulated by chlorophyllin and ellagic acid supplementation.

Functional classification	Genes Symbols
Chlorophyllin/Ellagic acid- upregulated
HSA04514_Cell adhesion molecules	NRCAM, CLDN1, NRXN1
HSA03320_PPAR signaling pathway	UBC, HMGCS2
Hsa04080_Neuroactive ligand receptor interaction	OPRM1, P2RX2, GLP1R, EDG5, DRD4
Chlorophyllin/Ellagic acid- downregulated
HSA04350_TGF beta signaling pathway	TGFB1
Hsa03050_Proteasome	PSMA7

Genes commonly modulated by chlorophyllin and ellagic acid in the enriched pathways (z-score >2) are listed. Gene enrichment analysis was done using GSEA Pre Ranked Tool. P value correction was done using Benjamini and Hochberg method.