Predictions are based on data from the MemPype prediction site (http://mu2py.biocomp.unibo.it/mempype). Putative
transmembrane domains are underlined and the amino acids to which the GPI is
predicted to be attached are boxed. Shaded amino acids are those that differ
from the consensus sequence. The most likely mode of membrane anchoring is
indicated on the right side of the figure. The alignment was created using
ClustalW implemented in the Lasergene software package (DNAStar Inc,
Madison, WI). Accession numbers of sequences used for the alignment were :
Mouse, AAM47034; rat, NP_001094437 ;human, AAG42685; Chimpanzee,
XP_001138632 ; Orangutan, XP_002831599.1; Gibbon, XP_003271059; Rhesus
monkey, XP_001087613; Domestic cow, XP_002700268; rabbit, XP_002719884;
Zebrafish, ABB03696; Xenopus, NP_001087744; Anolis, XP_003219032; and
zebrafinch, XP_002190541.