Figure 3. P_Rv0560c induction by structural analogs of salicylate in M. tuberculosis.

Promoter activity was measured in M. tuberculosis transformants grown under aerobic growth conditions. A. Promoter activity of P_Rv0560c after treatment with 0.4 mM of compound for 3 d. Results are the average and standard deviation of three independent transformants assayed in duplicate. Activity is given in Miller Units. B. Chemical structures of compounds of interest. A significant difference compared using Student's t-test to the untreated control is marked by an * for p<0.05) ** for p<0.01, *** for p<0.0001.