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. 2012 Apr 2;197(1):27–35. doi: 10.1083/jcb.201111053

Figure 2.

Figure 2.

Q cell corpse engulfment is normal, but its degradation in phagocytes is defective. (A) Still images of the birth, engulfment, and degradation of the Q cell corpse in WT. (top) Q cell plasma membrane and chromosome are imaged by mCherry. (middle) The actin in a hyp7 cell is labeled by GFP. The merged images are shown on the bottom. (B) Q cell corpse in the atg-18 (top) or epg-5 (bottom) mutant. The birth of the apoptotic Q cell was the end of cytokinesis of their mother (arrows; the cleavage furrows in the left of A and B). The engulfment of the apoptotic Q cell was the last frame with actin halo (arrows in the middle of A and B). The degradation was the last frame showing Q cell corpse (arrows in the right of A and B). Anterior of the cell is to the left. (C) Quantifications of the time for Q cell corpse engulfment and degradation. n = 10–29 from a single experiment. Statistical analysis was shown in Fig. S2 (A and B). Bars, 2.5 µm.