Figure 4.
The effect of long-term acetate supplementation on the expression of individual brain histone deacetylase in control rats (aCSF), rats subjected to neuroinflammation (LPS) and rats treated with either water (H2O) or glyceryl triacetate (GTA). (A) Representative images of the western blots. (B) Quantifications of HDAC1, 2, 3, 4, 5 and 7. Data in B represent means ± SD of the optical densities normalized to α-tubulin. Statistical significance (* compared to aCSF + H2O controls) was set at P ≤ 0.05, as determined by one-way ANOVA followed by Tukey's post-hoc test for HDAC2, 3, 4 and 5, and nonparametric one-way ANOVA followed by Dunn's post-hoc test for HDAC1 and 7.