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. 2012 Apr 3;10(4):e1001298. doi: 10.1371/journal.pbio.1001298

Figure 3. en controls Hh protein levels and Hh secretion is required for GSC maintenance.

Figure 3

(A) Control germarium. Hh is expressed specifically in TFCs and CpCs. (B) en E mutant CpC showing a strong decrease in Hh levels. (C and D) hh AC (C) or disp SH21 (D) mutant CpCs can induce GSC differentiation, as visualised by the presence of differentiating cysts adjacent to CpCs. See also Figure S3 and Table S2. Ovaries of the appropriate genotypes were dissected 3 d after eclosion. White open arrowheads, wild-type TFCs; yellow open arrowheads, wild-type CpCs; yellow arrowheads, mutant CpCs; white dashed lines, differentiating cysts in contact with CpCs. Scale bars: 10 µm.