Figure 2. Effect of aspartame consumption on spatial learning in C57BL/6J mice: gender-specific differences.

Acquisition curves of escape latency in male (A) and female (B) aspartame-fed and control diet mice. Percentage time spent in target quad in male (C) and female (D) mice. Mean Distance to goal in male (E) and female (F) mice. Each group consisted of 12 mice; * P<0.05, ** P<0.01, *** P<0.001.