Skip to main content
. 2012 Apr 3;7(4):e34129. doi: 10.1371/journal.pone.0034129

Table 2. Social interaction.

Parameter WT Nrg1 TM HET
Vehicle CBD 1 CBD 50 CBD 100 Vehicle CBD 1 CBD 50 CBD 100
Nosing [n] 40.7±2.4 41.5±2.4 42.4±3.2 46.1±2.5 43.4±2.9 50.2±3.7 * 52.0±3.5 * 48.2±3.2
Nosing duration [s] 46.6±2.0 44.9±4.1 47.8±3.2 55.2±5.1 41.5±2.7 45.3±3.1 62.4±6.0 ## 51.6±5.8
Anogenital sniffing [n] 21.1±1.7 18.5±2.2 21.5±2.3 25.2±2.8 17.8±2.0 21.3±2.8 29.4±2.6 ## 26.2±3.4
Anogenital sniffing duration [s] 20.3±2.1 19.0±2.8 23.4±3.3 27.2±3.1 14.4±1.9 19.3±3.1 29.9±3.6 ## 23.3±1.9 ##
Total social interaction duration [s] 74.4±5.5 67.1±6.4 76.7±6.8 86.6±7.6 60.2±4.1 67.0±6.1 98.8±10.3 ## 84.8±10.3

Frequency and duration of nosing and anogenital sniffing with a standard opponent A/JArc mouse after injection with CBD (1, 50 or 100 mg/kg). Data represent means (± S.E.M.). Significant one-way ANOVA (split by corresponding factor) results are shown:

*

P<0.05 (vs. WT receiving corresponding treatment);

##

P<0.01 (vs. vehicle of corresponding genotype).