Table 4. Test biography of mice.
Test/Treatment Day | Test |
1 | Light-dark test (LD), open field (OF), prepulse inhibition (PPI) |
13 | OF |
14 | Novel object recognition test (NORT) habituation trials 1–2 |
15 | LD, NORT habituation trial 3 |
16 | NORT habituation trials 4–5 |
17 | NORT test trials 1–2 |
19 | Social interaction |
21 | PPI |
WH | OF, LD, PPI |
126 mice were injected with either vehicle or CBD (1, 50 or 100 mg/kg body weight) once daily from test day 1–21 (n = 14–17). Animals were tested again in OF, LD and PPI 48 h after the completion of the chronic CBD administration (WH day = test day 23).