Table.
Expression of TRPV and ASICs in Trigeminal Ganglion Neurons Innervating Different Craniofacial Tissues and Their Co-expression with CGRP and P2X3
| Receptor/Channel | TG Neurons (%) | Cutaneous (%) | Tooth Pulp (%) | Jaw Joint (%) | Muscle* (%) |
|---|---|---|---|---|---|
| TRPV1 (VR-1) | 201 | 261 | 81 | 254 | 666 |
| TRPV2 (VRL-1) | 142 | 92 | 362 | 414 | — |
| ASIC3 | 23 | 13 | 33 | — | 646 |
| TRPV1 & P2X3 | 35% of P2X33 | 163 | 63 | — | 506 |
| TRPV1 & CGRP | 571 | 181 | 1001 | 38% of CGRP4 | — |
| TRPV2 & P2X3 | 9% of P2X33 | 83 | 233 | - | — |
| TRPV2 & CGRP | — | 252 | 452 | 30% of CGRP4 | — |
| ASIC3 & CGRP | 265 | 37% of CGRP5 | 36% of CGRP5 | — | — |
| TRPV1, ASIC3 & P2X3 | — | - | - | — | 56 |
*
Electrophysiological study.