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. 2012 Apr 3;7(4):e34355. doi: 10.1371/journal.pone.0034355

Figure 6. Relative mRNA quantification of IL-12Rβ2 mRNA expression in tuberculosis patients (N = 28).

Figure 6

Histogram shows the IL-12Rβ2 mRNA expression profile in the blood of the tuberculosis patients. The identification of the polymorphism at −237 site has been carried out by PCR amplification and sequencing (forward & reverse) of the 622 bp region spanning −780 to −159. The patients with the T at −237 polymorphic site has been indicated. The bars represent expression of IL-12Rβ2 mRNA in each individual. The fold activity pattern in real time PCR assay was calculated as described in methods, [15]. The individuals with reduced / elevated IL-12Rβ2 mRNA expression have been designated as Low expressers / High expressers.