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Pre-meiotic female germ cells express CCND1. CCND1 is expressed prior to meiosis and is repressed in an anterior-to-posterior wave. Confocal microscopy images of E12.5 to E15.5, Oct4::GFP transgenic ovaries immunostained for CCND1. Dotted lines indicate the boundary at which germ cells transition from CCND1-negative to CCND1-positive. Small groups of CCND1-positive germ cells are noted (arrowheads). The anterior (A) to posterior (P) axis is indicated. Scale bars: 150 μm.
