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. 2012 Apr 3;7(4):e34559. doi: 10.1371/journal.pone.0034559

Table 1. Reduction in Lmo4 levels does not affect anxiety-like behavior.

Behavior Parameter measured WT Lmo4gt/+ shLmo4 shScr
Elevated Plus Maze % Open Arm Entries 41.14±3.03 40.41±2.23 36.54±3.5 37.66±3.76
% Time in Open Arms 19.42±3.81 22.72±3.43
29.84±3.98 27.62±4.87
Light/Dark Box % Time in Lit Compartment 35.44±1.68 38.63±6.62 29.7±4.18 29.5±3.6
Open Field % Time Spent in Center 16.77±1.85 12.74±1.44 9.92±1.47 10.56±1.48
Distance Traveled (cm) 1028.2±61.81 817.91±90.89 1118.39±86.65 1031.17±68.48

The effects of global (Lmo4gt/+) or adult-and brain region-specific knockdown of Lmo4 in the BLC on anxiety-like behavior was examined. Mice were subjected to the elevated plus maze, light/dark box, or the open field test. Mean values ± SEM are depicted. N = 11–12 (WT) and 9–11 (Lmo4gt/+) mice and n = 9–10 for shLmo4 and 10 for ShScr injected mice.