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. 2012 Apr 3;7(4):e34984. doi: 10.1371/journal.pone.0034984

Table 1. Relationship between LAPTM4B genotypes and clinicopathological features of HCC.

Variables Patients LAPTM4B genetype Pa
*1/1 *1/2 *2/2
Gender 0.172
Male 57 16 32 9
Female 11 6 3 2
Age (years) 0.415
<65 44 14 21 9
≥65 24 8 14 2
Viral status 0.171
Hepatitis virus B 49 16 22 11
Hepatitis virus C 12 3 9 0
Both hepatitis virus B and C 2 0 2 0
Non-B, Non-C 5 3 2 0
Tumor size 0.852
<5 cm 37 13 18 6
≥5 cm 31 9 17 5
portal vein invasion 0.001
No 49 22 22 5
Yes 19 0 13 6
Histopathological differentiation 0.009
WD 20 12 6 2
MD 25 8 14 3
PD 23 2 15 6
Serum AFP level 0.144
<25 ng/ml 35 14 18 3
≥25 ng/ml 33 8 17 8
TNM stage <0.001
I–II 23 18 4 1
III–IV 45 4 31 10
Recurrence <0.001
No 17 12 5 0
Yes 51 10 30 11

LAPTM4B, Lysosomal protein transmembrane 4 beta; HCC, hepatocellular carcinoma; a, Chi-square test.