Table 1.

Overview of Clinical and Laboratory Procedures Performed During Each Study Visit

	Screening Visit	Dental Cleaning	Control Phase				Experimental Phase				Recovery Phase
Day of phase			0	7	14	21	0	7	14	21	0	7	14	21
Day of study	0	7	14	21	28	35a	35a	42	49	56b	56b	63	70	77
Visit number	1	2	3	4	5	6	6	7	8	9			10	11
Blood draw			X	X	X	X	X	X	X	X			X	X
Plaque and gingivitis assessment			X	X	X	X	X	X	X	X			X	X
Dental prophylaxis		X								Xc
Oral hygiene instruction		X	X	X	X					X

^aSame day of study.

^bSame day of study.

^cDental prophylaxis scheduled no more than 2 days after Day 21 of the experimental phase.