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Pancreatic transgene expression at one week after cyclin D2/CDK4/GLP-1 gene delivery by UTMD (animals killed at one week after UTMD). Cyclin D2 and CDK4 signal is seen in the cytoplasm and nucleus of insulin- and glucagon-positive cells only; GLP-1 signal seen in the cytoplasm of insulin- and glucagon-positive cells. x400 magnification.
