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. 2012 Apr 4;102(7):1543–1550. doi: 10.1016/j.bpj.2012.01.042

Figure 3.

Figure 3

Shift in cluster life times is transient for Phalloidin. (A) Lifetime of MHC-I clusters from cells incubated with 20 μM Phalloidin (identical with Fig. 2, bottom panel) imaged immediately after removing the drug. (B) Lifetime of MHC-I clusters from same cells, 30 min after removing the drug. (C) Lifetime of MHC-I clusters from untreated cells. (Solid lines) Fit to log-normal distribution. (Vertical dashed line) Mode (peak) of the distribution for 20 μM Phalloidin treatment. (Arrows) Gradual shift toward shorter lifetimes, as the effect of Phalloidin is reduced.