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. 2012 Apr;62(2):87–94.

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Figure 3. — (A) Compared with wildtype controls (n = 5; open squares), RCAN1-knockout mice (n = 7; closed squares) spend significantly more time (mean ± SEM) exploring the open arms (+, P = 0.006) and less time in the closed portion (*, P = 0.044) of the elevated-plus maze, demonstrating decreased anxiety. (B) Compared with wildtype controls (n = 8; open squares), Tg-RCAN1^TG mice (n = 8; closed squares) spend significantly more time (mean ± SEM) in the closed portion (+, P = 0.006) and less time exploring the open arms (*, P = 0.028), demonstrating an increased level of anxiety.