Table 1.
Characteristics of 246 HIV-infected patients at tuberculosis diagnosis and outcome of treatment.
| Variable | n (%) | Successful outcome n (%) |
Death n (%) |
Unsuccessful outcome n (%) |
P value |
|---|---|---|---|---|---|
| Sex | |||||
| Male | 199 | 97 (48.7) | 32 (16.1) | 70 (35.2) | 0.035 |
| Female | 47 | 33 (70.2) | 4 (8.5) | 10 (21.3) | |
| Place of origin | |||||
| Born in Italy | 162 | 84 (51.9) | 29 (17.9) | 49 (30.2) | 0.11 |
| Foreign born | 84 | 46 (54.8) | 7 (8.3) | 31 (36.9) | |
| Age at TB diagnosis (years) | |||||
| <40 | 162 | 87 (53.7) | 18 (11.1) | 57 (35.2) | 0.084 |
| ≥40 | 84 | 43 (51.2) | 18 (21.4) | 23 (27.4) | |
| Education (years) | |||||
| 0–8 | 146 | 75 (51.4) | 21 (14.4) | 50 (34.2) | 0.850 |
| 9–18 | 51 | 26 (51.0) | 9 (17.6) | 16 (31.4) | |
| Unknown | 49 | 29 (59.2) | 6 (12.2) | 14 (28.6) | |
| History of imprisonment | |||||
| Yes | 24 | 12 (50.0) | 4 (16.7) | 8 (33.3) | 0.91 |
| No/unknown | 222 | 118 (53.2) | 32 (14.4) | 72 (32.4) | |
| Mode of HIV infection | |||||
| Injecting drug use | 119 | 49 (41.2) | 25 (21.0) | 45 (37.8) | 0.001 |
| Other | 127 | 81 (63.8) | 11 (8.7) | 35 (27.6) | |
| Housing | |||||
| Private | 209 | 116 (55.5) | 33 (15.8) | 60 (28.7) | 0.014 |
| Community/homeless | 37 | 14 (37.8) | 3 (8.1) | 20 (54.1) | |
| CD4 lymphocyte count (cells/mmc) | |||||
| 0–199 | 156 | 81 (51.9) | 26 (16.7) | 49 (31.4) | 0.18 |
| 200–350 | 42 | 20 (47.6) | 8 (19.0) | 14 (33.3) | |
| >350 | 48 | 29 (60.4) | 2 (4.2) | 17 (35.4) | |
| AIDS | |||||
| Yes | 132 | 65 (49.2) | 27 (20.5) | 40 (30.3) | 0.019 |
| No | 114 | 65 (57.0) | 9 (7.9) | 40 (35.1) | |
| Site of diseases | |||||
| Pulmonary | 197 | 101 (51.3) | 28 (14.2) | 68 (34.5) | 0.413 |
| Extra pulmonary | 49 | 29 (59.2) | 8 (16.3) | 12 (24.5) | |
| History of TB treatment | |||||
| New cases | 206 | 113 (54.9) | 28 (13.6) | 65 (31.6) | 0.279 |
| Previously treated cases | 40 | 17 (42.5) | 8 (20.0) | 15 (37.5) | |
| Drug susceptibility test# | |||||
| Susceptible TB | 99 | 54 (54.5) | 15 (15.2) | 30 (30.3) | 0.387 |
| DRTB | 22 | 13 (59.1) | 2 (9.1) | 7 (31.8) | |
| MDR TB | 4 | 1 (25.0) | 2 (50.0) | 1 (25.0) | |
| Awareness of HIV seropositivity | |||||
| Yes | 176 | 79 (44.9) | 31 (17.6) | 66 (37.5) | <0.001 |
| No | 70 | 51 (72.9) | 5 (7.1) | 14 (20.0) | |
| cART naive | |||||
| Yes | 150 | 84 (56.0) | 16 (10.7) | 50 (33.3) | 0.091 |
| No | 96 | 46 (47.9) | 20 (20.8) | 30 (31.2) | |
| Concomitant diseases at TB diagnosis | |||||
| Yes | 60 | 30 (50.0) | 15 (25.0) | 15 (25.0) | 0.033 |
| No | 186 | 100 (53.8) | 21 (11.3) | 65 (34.9) |
#Calculated on 125 patients with drug susceptibility test performed.