Table 2.
Multivariable odds ratios* of unsuccessful outcome of tuberculosis treatment and death according to baseline characteristics for 246 HIV-infected patients with tuberculosis.
| Variable | Unsatisfactory outcome of TB treatment | Death | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Sex | ||||
| Male | 1.00 | 1.00 | ||
| Female | 0.38 (0.16–0.90) | 0.029 | 0.35 (0.10–1.27) | 0.112 |
| Place of origin | ||||
| Born in Italy | 1.00 | 1.00 | ||
| Foreign born | 3.66 (1.48–9.06) | 0.005 | 1.98 (0.52–7.45) | 0.314 |
| Age at TB diagnosis (years) | ||||
| <40 | 1.00 | 1.00 | ||
| ≥40 | 1.04 (0.52–2.11) | 0.909 | 2.34 (0.94–5.84) | 0.068 |
| Education (years) | ||||
| 0–8 | 1.00 | 1.00 | ||
| 9–18 | 1.00 (0.44–2.27) | 0.996 | 0.81 (0.27–2.37) | 0.698 |
| Unknown | 0.83 (0.35–1.96) | 0.671 | 0.69 (0.20–2.35) | 0.550 |
| History of imprisonment | ||||
| Yes | 1.00 | 1.00 | ||
| No/unknown | 1.93 (0.65–5.74) | 0.238 | 2.17 (0.53–8.90) | 0.282 |
| Mode of HIV infection | ||||
| Injecting drug use | 1.00 | 1.00 | ||
| Other | 0.42 (0.19–0.93) | 0.033 | 0.25 (0.08–0.74) | 0.012 |
| Housing | ||||
| Private | 1.00 | 1.00 | ||
| Community/homeless | 2.21 (0.93–5.30) | 0.074 | 0.44 (0.09–2.30) | 0.333 |
| CD4 lymphocyte count (increase: 50 cells) | 0.96 (0.88–1.04) | 0.326 | 0.83 (0.71–0.97) | 0.020 |
| AIDS | ||||
| Yes | 1.00 | 1.00 | ||
| No | 0.90 (0.45–1.82) | 0.778 | 0.44 (0.16–1.19) | 0.106 |
| Site of diseases | ||||
| Pulmonary | 1.00 | 1.00 | ||
| Extra pulmonary | 0.66 (0.29–1.50) | 0.320 | 1.15 (0.42–3.18) | 0.782 |
| History of TB treatment | ||||
| New cases | 1.00 | 1.00 | ||
| Previously treated cases | 0.96 (0.39–2.36) | 0.930 | 0.71 (0.22–2.32) | 0.572 |
| Drug susceptibility test | ||||
| Susceptible TB | 1.00 | 1.00 | ||
| DR TB | 1.03 (0.33–3.21) | 0.962 | 0.44 (0.07–2.69) | 0.376 |
| MDR TB | 0.83 (0.03–20.52) | 0.911 | 37.10 (1.98–693.79) | 0.016 |
| Not available | 1.41 (0.71–2.78) | 0.322 | 1.24 (0.50–3.07) | 0.649 |
| Awareness of HIV seropositivity and HIV treatment history | ||||
| Not aware | 1.00 | 1.00 | ||
| Aware and cART naive | 5.11 (2.04–12.80) | 0.001 | 2.95 (0.77–11.33) | 0.115 |
| Not cART naive | 3.31 (1.29–8.46) | 0.013 | 4.04 (1.09–14.96) | 0.037 |
| Concomitant diseases at TB diagnosis | ||||
| Yes | 1.00 | 1.00 | ||
| No | 1.38 (0.59–3.26) | 0.461 | 0.59 (0.23–1.55) | 0.286 |
*From polytomous logistic regression model with successful outcome as reference category.