Table 4.
Qualitative assessments of bacteria in tissues
| Tissue | No. (%) of animals positive for Y. pestis in each tissue at each collection point, h postchallenge |
|||||
|---|---|---|---|---|---|---|
| 12 | 24 | 36 | 48 | 60 | 72 | |
| Lung | 20 (100) | 18 (90) | 19a (100) | 20 (100) | 20 (100) | 20 (100) |
| Liver | 0 (0) | 8 (40) | 13 (65) | 17 (85) | 18 (90) | 17 (85) |
| Kidney | 0 (0) | 16 (80) | 11 (55) | 16 (80) | 13 (65) | 17 (85) |
| Spleen | 0 (0) | 2 (10) | 8 (40) | 17 (85) | 16 (80) | 17 (85) |
| Bloodb | No | Yes | Yes | Yes | Yes | Yes |
a
This group contained 19 mice. All other groups contained 20 mice.
b
Bacteremia was determined by pooling samples by group. Only female mice were bacteremic at 24 h postchallenge; both male and female mice were bacteremic at subsequent time points.