Fig 4.

Summary of experimentally confirmed and projected values based on canine patient sera for antibodies to OspC, OspF, and C6 antigens of B. burgdorferi during early and late infection. The data were obtained by multiplex analysis. The lines for the first 3 months after infection are based on the multiplex results from experimentally infected dogs. After 3 months the lines are projected from the data obtained from patient serum. The horizontal dotted line shows the cutoff value for the multiplex assay. The vertical dotted line indicates 3 months after infection.