Fig 5.

The cells responding to S. aureus immunization are predominantly CD4 T cells. Two-week cell lines were undepleted or depleted of CD4⁺ cells or CD8⁺ cells and γδ T cells. Heat-killed S. aureus (5 × 10⁶ bacteria/well) was used as the antigen. Responses are presented as the SI compared to medium ± 1 SD for triplicate cultures. Significant responses of each cell population are indicated with asterisks, where P is <0.05 using a one-tailed Student's t test.