Figure 2.

Induction of gob-5 before the onset of AHR and eosinophilic inflammation. (A) Time-related changes in airway responsiveness after OVA inhalation were measured (n = 7–11). **, P < 0.01, compared with day 0 group. (B) Time-related changes in cell recruitment in BAL fluid after OVA inhalation. BAL was performed 24 h after inhalation of aerosolized OVA (n = 6–7). Total cells (●) were classified as macrophages (■), eosinophils (▴), neutrophils (○), or lymphocytes (□). (C) Time-dependent expression of gob-5 was determined by Northern blot analysis in lung tissue after OVA inhalation. Presented figures are representative of three separate experiments. Three different experiments showed similar results.