Fig 7.

Strain carrying sen1-R302W causes altered transcriptional occupancy of Sen1. ChIP-chip traces of Ser₂-P, Ser₅-P, and Ser₇-P (top panels) and Sen1-cMyc, Sen1-R302W-TAP, and Ser₂-P CTD (bottom panels) over the polycistronic snoRNA cluster SNR78-72 (A) and the protein-coding gene PSA1 (B). Black arrows denote the transcriptional start sites (TSS). Black bars within the transcribed region show the mature snoRNA transcripts in SNR78-72 and the protein-coding region of PSA1. In PSA1, the blue bar denotes the cleavage and polyadenylation site. The scale used for the right y axis corresponds to the Ser₅-P profile.