Fig 5.

Sam37 is required for virulence of C. albicans in the mouse systemic candidiasis model. (A) Mice were infected with the C. albicans strains via the tail vein, and disease progression was monitored as described in Materials and Methods. Differences in survival were assessed by the Kaplan-Meier method (P < 0.05). (B) Kidney histopathology was performed at day 1 of the infection, and C. albicans cells were visualized by PAS staining. Arrows indicate C. albicans cells found in the infected kidneys.