Table 1.
Antibiotic susceptibilities for NDM-1-positive and -negative isolates from the same patient
| Antibioticb | MICa (μg/ml) |
|||
|---|---|---|---|---|
| P. stuartii (MRSN 2154/2155) | P. aeruginosa (MRSN 2152) | P. aeruginosa (MRSN 2153) | P. mirabilis (MRSN 2150) | |
| Tobramycin | >8 | >8 | >8 | ≤1 |
| Ampicillin-sulbactam | >16/8 | >16/8 | >16/8 | 16/8 |
| Piperacillin-tazobactam | >64/4 | >64/4 | >64/4 | ≤2/4 |
| Cefepime | >16 | >16 | >16 | ≤2 |
| Cefoxitin | >16 | >16 | >16 | ≤4 |
| Ceftazidime | >16 | >16 | >16 | ≤2 |
| Ceftriaxone | >32 | >32 | >32 | ≤2 |
| Aztreonam | ≤2 | >16 | >16 | ≤2 |
| Colistinc | >256 | - | 2 | - |
| Ertapenem | >4 | - | - | ≤0.5 |
| Imipenem | >8 | ≤4 | >8 | ≤4 |
| Meropenem | >8 | ≤4 | ≥16 | ≤4 |
| Ciprofloxacin | >2 | 2 | >2 | >2 |
| Levofloxacin | >4 | 4 | >4 | >4 |
| Tetracycline | >8 | >8 | >8 | - |
| Tigecyclinec | 4 | - | - | - |
| Trimethoprim-sulfamethoxazole | >2/38 | - | - | >2/38 |
a
MICs were confirmed and replicated on Vitek2, Phoenix, and Microscan automated systems.
b
All isolates were resistant to gentamicin. A dash indicates not tested or inherently resistant.
c
Etest result.