Table 1.
Characteristics of A. baumannii isolates
Isolate | Hospital/clonalitya | MLST | Resistance profileb | blaOXA-51-like | Acquired CHDL | Gene cassettes of class 1 integron | Other genes conferring antibiotic resistance | AbaR length (kb) |
---|---|---|---|---|---|---|---|---|
LT-3 | K/clonal | ST2 | MEM IPM TZP CAZ AN CIP PIP | OXA-66 | OXA-72 | tetB, strA, strB | 18 | |
LT-11 | K/sporadic | ST2 | MEM IPM TZP SAM CAZ GM AN CIP PIP | OXA-66 | OXA-23 | aacA4-catB8-aadA1 | tetB, strA, strB, aphA1, armA, adeABC | 23 |
LT-V1 | V/clonal | ST2 | MEM IPM TZP CAZ GM AN CIP PIP | OXA-66 | OXA-72 | aacC1c | tetB, strA, strB, adeABC | 21 |
K, Lithuanian University of Health Sciences Kauno Klinikos Hospital; V, Vilnius University Emergency Hospital. LT3 and LT-V1 were representative isolates of clonal outbreaks in hospitals in 2010, whereas LT-11 was a sporadic isolate. Clonality was determined by PFGE-ApaI restriction analysis.
Antimicrobial susceptibility to MEM (meropenem), IPM (imipenem), TZP (tazobactam/piperacillin), SAM (sulbactam/ampicillin), SCF (sulbactam/cefoperazone), CAZ (ceftazidime), GM (gentamicin), AN (amikacin), CIP (ciprofloxacin), and PIP (piperacillin) was tested.
The 3′-conserved segment (CS) of integron was missing.