Table 2.
Summary of genes responding to cell wall integrity
Phenotype | Genes |
---|---|
Micafungin sensitivity | apm1,eaps3,evps45,epub1,epal1,evps1,bsft1,bada3,bcph1,bpka1,bgpa2,bgit1,brpl2001,b SPBC25D12.06,brkr1,a,brrd1,a,bkti12,a,birc6,a,bccr4,cgos1,cbrl2,cddb1,cnut2,cend4,crpl3202,ccip2,cugp1,a,cgga1,a,cent3,aerd1,apuf1,asts1, spo9, kes1, apl6, apm3, sip1, lsd1, SPBC725.10, SPCC126.13c, cdt2, SPBC14F5.10c, rho2, rnc1, yox1, rep2, iws1, aah3, SPAC1071.11, rhp51, trt1, iki3, mug14, pds5, rph54, uge1, SPAC57A10.08c |
Osmoremedial ergosterol biosynthesis inhibitor sensitivity | apm1,eaps3,evps45,epub1,epal1,evps1,bsft1,bada3,bcph1,bpka1,bgpa2,bgit1,brpl2001,b SPBC25D12.06,brkr1,a,brrd1,a,bkti12,a,birc6,a,b SPCC297.05,dada2,dapl5,dnog2,apng1,athp3,awwm1,agcs1,avps32, uga4, gms1, zhf1, cat1, ppk33, git5, cgr1, sdh1, cys12, dga1, atg4, SPCC1020.07, SPAC56E4.07, SPAC22F8.03c |
β-Glucanase sensitivity | apm1,eaps3,evps45,epub1,epal1,egos1,cbrl2,cddb1,cnut2,cend4,crpl3202,ccip2,cugp1,a,cgga1,a,cccr4,cada2,d SPCC297.05,dapl5,dlee1,afta5, spt8, kap1, cch1, sft2 |
The common name is taken from the orthology of S. cerevisiae.
The gene disruption exhibited two of the three phenotypes, that is, micafungin sensitivity and osmoremedial ergosterol biosynthesis inhibitor sensitivity.
The gene disruption exhibited two of the three phenotypes, that is, micafungin sensitivity and β-glucanase sensitivity.
The gene disruption exhibited two of the three phenotypes, that is, osmoremedial ergosterol biosynthesis inhibitor sensitivity and β-glucanase sensitivity.
Genes by which gene disruption exhibited all three phenotypes, that is, micafungin sensitivity, osmoremedial ergosterol biosynthesis inhibitor sensitivity, and β-glucanase sensitivity.