Table 1.
Susceptibilities to β-lactams of P. aeruginosa and E. coli strains harboring gene blaIMP-29
| β-Lactam | MIC (μg/ml) for strain |
||||||
|---|---|---|---|---|---|---|---|
|
P. aeruginosa |
E. coli |
||||||
| 10.266 | 10.298 | PU21(pIMP266) | PU21 | DH5α(pK-IMP29) | DH5α(pK-IMP266) | DH5α(pK18) | |
| Amoxicillin | >256 | >256 | >256 | >256 | 64 | 128 | 0.5 |
| Ticarcillin | >256 | >256 | 256 | 8 | 256 | >256 | 0.5 |
| Piperacillin | 256 | 256 | 8 | 2 | 1 | 2 | ≤0.06 |
| Cefotaxime | >256 | 256 | >256 | 8 | 4 | 16 | ≤0.06 |
| Ceftazidime | >256 | 128 | 256 | 1 | 16 | 64 | ≤0.06 |
| Cefepime | >256 | 64 | 256 | 1 | 0.5 | 4 | ≤0.06 |
| Imipenem | 128 | 64 | 8 | 1 | 0.5 | 1 | 0.12 |
| Meropenem | >256 | 128 | 64 | 0.5 | 0.25 | 4 | ≤0.06 |
| Doripenem | >256 | 64 | 64 | 0.25 | 0.25 | 4 | ≤0.06 |
| Ertapenem | >256 | 256 | 256 | 8 | 0.12 | 4 | ≤0.06 |
| Aztreonam | 8 | 4 | 4 | 2 | ≤0.06 | 0.12 | ≤0.06 |